HRT Defintion

HRT

Hormone Replacement Therapy in the UK


Are you wondering if you should consider hormone replacement therapy (HRT) or not? Read this article to learn about the indications and contraindications of HRT and how you can take it.


Introduction

Both men and women have a set of hormones in the body that help build their primary and secondary sexual characteristics. Hormone replacement therapy (HRT) is needed when your body cannot make enough hormones to function properly. It helps balance hormone levels to improve your overall health.

Why is Hormone Replacement Therapy Used?

Hormone Replacement Therapy (HRT) is useful, especially in treating menopausal symptoms like hot flashes, restless legs, insomnia, osteoporosis, etc.

There has been a surge in the usage of HRT in various medical conditions for both men and women. Recent statistics say that around 1.93 million people were prescribed HRT in the UK in 2021.

There are Different Types of Hormones in HRT

Both men and women need different sexual hormones to maintain their overall health. So, different hormones are used in HRT:

-      Estrogen

-      Progesterone

-      Testosterone

Types of Available Hormone Replacement Therapy (HRT) in the UK

HRT is given in different forms based on your condition.

Estrogen-only HRT

This type contains only estrogen. It helps reduce menopause symptoms and strengthens bones, which can become weak due to low estrogen levels during menopause.

Your doctor might suggest estrogen-only HRT if you’ve had a hysterectomy (removal of the womb).

Some estrogen HRT brand names include:

-      Sandrena

-      Lenzetto

-      Evorel

-      FemSeven

-      Oestrogel

-      Progynova

-      Elleste-Solo

-      Estradot

Combined HRT

It is recommended to prevent uterine (womb) cancer in females. You can take estrogen and progesterone either separately or together in one therapy. If taken separately, you have options:

-      Micronised progesterone tablets can be taken with estrogen patches, gel, spray, or tablets. This type of progesterone is plant-based and matches the progesterone your ovaries produce before menopause. This is called body-identical hormone replacement therapy.

-      An intrauterine device (IUS or coil, like the Mirena coil) can provide progesterone and be used with estrogen patches, gel, spray, or tablets. This may help reduce bleeding issues with HRT.

Alternatively, combined HRT, which contains estrogen and progesterone (as progestogen), is also available. One example is Bijuve, a bioidentical hormone replacement therapy, meaning it matches the natural hormones in your body.

Other combined HRT brands include:

-      Evorel Sequi

-      Novofem

-      Kliovance

-      Evorel

-      Kliofem

-      Elleste-Duet

-      Trisequens

-      Clinorette

-      Femoston

Tibolone (Livial®)

Tibolone is a form of combined hormone replacement therapy in the UK that works just like estrogen, progesterone and testosterone. It can help improve libido in some people.

The NHS recommends using it if you haven’t had your natural periods for 12 months consecutively.

Testosterone

Testosterone is a male hormone that will be prescribed if you have a low sex drive, and all other non-hormonal causes have been ruled out.

How is Hormone Replacement Therapy (HRT) in UK Given?

There are different ways to take HRT, depending on what works best for you:

-      Pills: Easy to take and common.

-      Patches: Stick to your skin and release hormones slowly.

-      Creams and Gels: Applied to your skin and absorbed.

-      Injections: Given with a needle, often with longer-lasting effects.

These options let you and your doctor choose the best method for your lifestyle and needs.

When is Hormone Replacement Therapy Indicated?

Indications of HRT are different for men and women.

For Women:

-      Treating menopausal symptoms like night sweats, hot flashes or mood swings.

-      Prevention of osteoporosis.

-      Management of symptoms in women who have had hysterectomy.

-      Improving quality of life.

For Men:

-      Treating hypogonadism.

-      Boosting energy levels and reducing fatigue.

-      Treating low testosterone symptoms like decreased libido, erectile dysfunction, and mood changes.

-      Preserving bone density in elderly males.

-      Improving muscle mass.

-      Enhancing cognitive function.

Who Should Not Take Hormone Replacement Therapy (HRT)?

Your doctor will not prescribe you HRT if you have or have had:

-      Womb (endometrial) or breast cancer

-      Blood clotting disease

-      Stroke

-      Heart attack

-      Liver conditions

-      Unexplained vaginal bleeding

-      Endometrial hyperplasia (thickening of the womb lining)

Takeaway Message: Hormone Replacement Therapy in UK

The HRT is an excellent option for treating hormone-related problems in menopausal females. Males can also benefit from HRT in various cases, such as if they have low libido, lean muscle mass, or reduced bone density.

HRT maintains the hormonal balance so you can enjoy a youthful life again.

 

Keyword: Hormone Replacement Therapy in UK

 References

  1. NHS. Hormone Replacement Therapy – England – April 2015 to June 2022. (2022). NHSBSA Statistics and Data Science.
  2. NHS. (2023). Who can and cannot take Tibolone? National Health Sciences.